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INF services are available to research scientists in universities, research institutes and pharmaceutical and biotech companies.
[Download list of INF services]
- Primary behavioural phenotyping
A primary screening to assess defects in CNS function in transgenic and knockout mice. Positive phenotypes may be further assessed using one or more of the specialised screens.
- Specialised behavioural phenotyping
A series of specialised test screens enables researchers to study defects relating to addiction and craving, memory and learning, anxiety and depression, motor function, pain and psychosis.
- Histology
Morphological phenotyping includes descriptions of major brain areas and cell density of mutant mice and following drug treatment.
- Immunohistochemistry
Mapping of protein expression in the brain using specific tagged antibodies, allowing both quantitative and qualitative measurement.
- Electrophysiology
Electrophysiological techniques, including the recording of physiological signals such as electroencephalograms, electromyograms and extracellular recordings in the behaving animal.
- Physiology
Techniques to measure blood pressure and heart rate, in vivo voltametry and biological assaying.
- Pharmacology
The various phenotyping tests can be assessed in response to the administration of agents.
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